FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ZNF364
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
33kDa
MW(Observed)
33kDa
推荐稀释比
WB 1:1000-1:5000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
PT1082R
特异性
Endogenous
基因名称
RNF115,ZNF364
蛋白名称
E3 ubiquitin-protein ligase RNF115 (EC 2.3.2.27) (RING finger protein 115) (RING-type E3 ubiquitin transferase RNF115) (Rab7-interacting RING finger protein) (Rabring 7) (Zinc finger protein 364)
别名
ZNF364
Organism-1
Human
基因ID-1
27246
SwissProt-1
Q9Y4L5
Organism-2
Mouse
基因ID-2
67845
SwissProt-2
Q9D0C1
背景
Enables ubiquitin protein ligase activity. Involved in negative regulation of signal transduction; protein ubiquitination; and ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Is active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2025]
细胞定位
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:20019814, ECO:0000269|PubMed:24852021}. Nucleus {ECO:0000269|PubMed:24852021}. Endoplasmic reticulum {ECO:0000269|PubMed:35343654}. Golgi apparatus {ECO:0000269|PubMed:35343654}. Note=The GTP-bound form of RAB7A recruits RNF115 from the cytosol onto late endosomes/lysosomes. {ECO:0000269|PubMed:20019814, ECO:0000269|PubMed:24852021}.
