- 产品信息
商品描述
靶点-Target
TXNIP
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG, Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
44kD
MW(Observed)
55kD
推荐稀释比
IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
PT1025R
特异性
Endogenous
基因名称
TXNIP VDUP1
蛋白名称
Thioredoxin-interacting protein (Thioredoxin-binding protein 2) (Vitamin D3 up-regulated protein 1)
别名
Thioredoxin-interacting protein;Thioredoxin-binding protein 2;Vitamin D3 up-regulated protein 1;
Organism-1
Human
基因ID-1
10628
SwissProt-1
Q9H3M7
Organism-2
Mouse
基因ID-2
56338
SwissProt-2
Q8BG60
Organism-3
Rat
基因ID-3
117514
SwissProt-3
Q5M7W1
背景
This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
细胞定位
Cytoplasm .





