TXNIP Rabbit mAb

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2621703

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商品描述
  • 靶点-Target

    TXNIP

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG, Kappa

  • 偶联-Conjugate

    Unmodified

  • MW(Calculated)

    44kD

  • MW(Observed)

    55kD

  • 推荐稀释比

    IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein A

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆号

    PT1025R

  • 特异性

    Endogenous

  • 基因名称

    TXNIP VDUP1

  • 蛋白名称

    Thioredoxin-interacting protein (Thioredoxin-binding protein 2) (Vitamin D3 up-regulated protein 1)

  • 别名

    Thioredoxin-interacting protein;Thioredoxin-binding protein 2;Vitamin D3 up-regulated protein 1;

  • Organism-1

    Human

  • 基因ID-1

    10628

  • SwissProt-1

    Q9H3M7

  • Organism-2

    Mouse

  • 基因ID-2

    56338

  • SwissProt-2

    Q8BG60

  • Organism-3

    Rat

  • 基因ID-3

    117514

  • SwissProt-3

    Q5M7W1

  • 背景

    This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

  • 细胞定位

    Cytoplasm .