Dnmt3a Rabbit mAb

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2621701

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商品描述
  • 靶点-Target

    DNM3A

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG, Kappa

  • 偶联-Conjugate

    Unmodified

  • MW(Calculated)

    102kD

  • MW(Observed)

    130kD

  • 推荐稀释比

    IHC 1:100-1:500;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein A

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆号

    PT1011R

  • 特异性

    Endogenous

  • 基因名称

    DNMT3A

  • 蛋白名称

    DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA)

  • Organism-1

    Human

  • 基因ID-1

    1788

  • SwissProt-1

    Q9Y6K1

  • Organism-2

    Mouse

  • SwissProt-2

    O88508

  • Organism-3

    Rat

  • SwissProt-3

    Q1LZ53

  • 背景

    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016],

  • 细胞定位

    Nucleus . Chromosome . Cytoplasm . Accumulates in the major satellite repeats at pericentric heterochromatin. .