- 产品信息
商品描述
靶点-Target
cIAP2
反应性
Human
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
68kD
MW(Observed)
68kD
推荐稀释比
IHC 1:200-1:500;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
PT0954R
特异性
Endogenous
基因名称
BIRC3
蛋白名称
Baculoviral IAP repeat-containing protein 3
别名
AIP 1;AIP1;API 2;API2;API2;Apoptosis inhibitor 2;Baculoviral IAP repeat containing 3;Baculoviral IAP repeat containing protein 3;Baculoviral IAP repeat-containing protein 3;BIRC 3;BIRC3;BIRC3;BIRC3_HUMAN;C IAP2;C-IAP2;CIAP 2;CIAP 2;CIAP2;HAIP 1;HAIP1;HAIP1;HIAP 1;HIAP-1;HIAP1;IAP homolog C;IAP-1;Inhibitor of apoptosis protein 1;Inhibitor of apoptosis protein 1;MALT 2;MALT2;Mammalian IAP homolog C;MIHC;MIHC;RING finger protein 49;RNF49;TNFR2 TRAF signaling complex protein 1;TNFR2 TRAF signalling complex protein;TNFR2-TRAF-signaling complex protein 1.
Organism-1
Human
基因ID-1
330
SwissProt-1
Q13489
Organism-2
Mouse
SwissProt-2
O08863
背景
This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011],
细胞定位
Cytoplasm . Nucleus .





