- 产品信息
商品描述
靶点-Target
IRAK 1
反应性
Human
应用
WB,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
77kD
MW(Observed)
77kD
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
PT0930R
特异性
Endogenous
基因名称
IRAK1
蛋白名称
Interleukin-1 receptor-associated kinase 1
别名
IRAK1;IRAK;Interleukin-1 receptor-associated kinase 1;IRAK-1
Organism-1
Human
基因ID-1
3654
SwissProt-1
P51617
Organism-2
Mouse
基因ID-2
16179
SwissProt-2
Q62406
背景
This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus . Lipid droplet . Translocates to the nucleus when sumoylated. RSAD2/viperin recruits it to the lipid droplet (By similarity). .





