FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ILK
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG, Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
51kD
MW(Observed)
51kD
推荐稀释比
IHC 1:500-1:2000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
PT0967R
特异性
Endogenous
基因名称
ILK
蛋白名称
Integrin-linked protein kinase
别名
ILK;ILK1;ILK2;Integrin-linked protein kinase;59 kDa serine/threonine-protein kinase;ILK-1;ILK-2;p59ILK
Organism-1
Human
基因ID-1
3611
SwissProt-1
Q13418
Organism-2
Mouse
基因ID-2
16202
SwissProt-2
O55222
Organism-3
Rat
基因ID-3
170922
SwissProt-3
Q99J82
背景
This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],
细胞定位
Cell junction, focal adhesion . Cell membrane; Peripheral membrane protein; Cytoplasmic side . Cell projection, lamellipodium . Cytoplasm, myofibril, sarcomere .
