FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Crk-L
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG, Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
34kD
MW(Observed)
39kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
PT0957R
特异性
Endogenous
基因名称
CRKL
蛋白名称
Crk-like protein
别名
CRKL;Crk-like protein
Organism-1
Human
基因ID-1
1399
SwissProt-1
P46109
Organism-2
Mouse
基因ID-2
12929
SwissProt-2
P47941
Organism-3
Rat
基因ID-3
287942
SwissProt-3
Q5U2U2
背景
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009],
细胞定位
endosome,cytosol,cell-cell adherens junction,extracellular exosome,
