- 产品信息
商品描述
靶点-Target
NDUFS1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG, Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
80kD
MW(Observed)
77kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
PT0942R
特异性
Endogenous
基因名称
NDUFS1
蛋白名称
NADH-ubiquinone oxidoreductase 75 kDa subunit mitochondrial
别名
NDUFS1;NADH-ubiquinone oxidoreductase 75 kDa subunit;mitochondrial;Complex I-75kD;CI-75kD
Organism-1
Human
基因ID-1
4719
SwissProt-1
P28331
Organism-2
Mouse
基因ID-2
227197
SwissProt-2
Q91VD9
Organism-3
Rat
基因ID-3
301458
SwissProt-3
Q66HF1
背景
The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011],
细胞定位
Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .





