- 产品信息
商品描述
靶点-Target
STML2
反应性
Human,Mouse,Rat
应用
WB,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
39kD
MW(Observed)
39kD
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
PT0947R
特异性
Endogenous
基因名称
STOML2 SLP2 HSPC108
蛋白名称
Stomatin-like protein 2 (SLP-2) (EPB72-like protein 2)
Organism-1
Human
基因ID-1
30968
SwissProt-1
Q9UJZ1
Organism-2
Mouse
基因ID-2
66592
SwissProt-2
Q99JB2
Organism-3
Rat
基因ID-3
66592
SwissProt-3
Q4FZT0
背景
Enables GTPase binding activity; T cell receptor binding activity; and cardiolipin binding activity. Involved in intracellular calcium ion homeostasis; mitochondrion organization; and protein complex oligomerization. Acts upstream of or within T cell receptor signaling pathway. Located in several cellular components, including immunological synapse; membrane raft; and mitochondrial envelope. [provided by Alliance of Genome Resources, Apr 2025]
细胞定位
Cell membrane ; Peripheral membrane protein . Mitochondrion . Mitochondrion inner membrane ; Lipid-anchor . Mitochondrion intermembrane space . Membrane raft . Cytoplasm, cytoskeleton . Behaves as an integral membrane protein of the mitochondrion despite the absence of a detectable transmembrane domain (PubMed:21746876). Also associates with the actin cytoskeleton and membrane rafts in activated T-cells (PubMed:18641330, PubMed:10713127). A minor pool is associated with the plasma membrane and is enriched at the immunological synapse in activated T-cells (PubMed:22623988). .





