FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TBK1
反应性
Human,Mouse,Rat
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Phospho
修饰-Modification
Ser172
MW(Calculated)
84kD
MW(Observed)
84kD
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
PT0905R
特异性
TBK1 (Phospho Ser172) Antibody detects endogenous levels of Tau protein only when phosphorylated at Ser172.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):FVsLY
基因名称
TBK1 NAK
蛋白名称
TBK1/NAK (Ser172)
别名
Serine/threonine-protein kinase TBK1;NF-kappa-B-activating kinase;T2K;TANK-binding kinase 1;
Organism-1
Human
基因ID-1
29110
SwissProt-1
Q9UHD2
Organism-2
Mouse
基因ID-2
56480
SwissProt-2
Q9WUN2
背景
The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010],
细胞定位
Cytoplasm . Upon mitogen stimulation or triggering of the immune system, TBK1 is recruited to the exocyst by EXOC2. .
