Histone H3 (Phospho Ser10/Thr11) Rabbit mAb
活动价:
市场价:¥1280.00
- 50μL
FAB2621643
- 产品信息
商品描述
靶点-Target
Histone H3
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG, Kappa
偶联-Conjugate
Phospho
修饰-Modification
Ser10/Thr11
MW(Calculated)
15kD
MW(Observed)
17kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
PT0977R
特异性
Histone H3 (Phospho Ser10/Thr11) Monoclonal Antibody detects endogenous levels of Histone H3 protein only when phosphorylated at Ser10/Thr11.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RKstGG
基因名称
HIST1H3A/HIST1H3B/HIST1H3C/HIST1H3D/HIST1H3E/HIST1H3F/HIST1H3G/HIST1H3H/HIST1H3I/HIST1H3J/HIST2H3A/HIST2H3C/HIST2H3D/H3F3A/H3F3B
蛋白名称
Histone H3.1/Histone H3.2/Histone H3.3
别名
HIST1H3A;H3FA;HIST1H3B;H3FL;HIST1H3C;H3FC;HIST1H3D;H3FB;HIST1H3E;H3FD;HIST1H3F;H3FI;HIST1H3G;H3FH;HIST1H3H;H3FK;HIST1H3I;H3FF;HIST1H3J;H3FJ;Histone H3.1;Histone H3/a;Histone H3/b;Histone H3/c;Histone H3/d;Histone H3
Organism-1
Human
基因ID-1
8350;8351;8352;8353;8354;8355;8356;8357;8358;8968
SwissProt-1
P68431;Q71DI3;P84243
Organism-2
Mouse
基因ID-2
319152;15077;15078
SwissProt-2
P68433
Organism-3
Rat
基因ID-3
291159;100361558
SwissProt-3
Q6LED0;P84245
背景
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015],
细胞定位
Nucleus. Chromosome.





