FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
OLIG2
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
32kD
MW(Observed)
38kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
PT0893R
特异性
Endogenous
基因名称
OLIG2 BHLHB1 BHLHE19 PRKCBP2 RACK17
蛋白名称
OLIG2
别名
Oligodendrocyte transcription factor 2;Oligo2;Class B basic helix-loop-helix protein 1;bHLHb1;Class E basic helix-loop-helix protein 19;bHLHe19;Protein kinase C-binding protein 2;Protein kinase C-binding protein RACK17;
Organism-1
Human
基因ID-1
10215
SwissProt-1
Q13516
Organism-2
Mouse
基因ID-2
50913
SwissProt-2
Q9EQW6
背景
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm . The NLS contained in the bHLH domain could be masked in the native form and translocation to the nucleus could be mediated by interaction either with class E bHLH partner protein or with NKX2-2. .
