FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
LXRα
反应性
Human,Mouse,Rat
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
50kD
MW(Observed)
50kD
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
PT0887R
特异性
Endogenous
基因名称
NR1H3
蛋白名称
Oxysterols receptor LXR-alpha
别名
NR1H3;LXRA;Oxysterols receptor LXR-alpha;Liver X receptor alpha;Nuclear receptor subfamily 1 group H member 3
Organism-1
Human
基因ID-1
10062
SwissProt-1
Q13133
Organism-2
Mouse
基因ID-2
22259
SwissProt-2
Q9Z0Y9
Organism-3
Rat
SwissProt-3
Q62685
背景
The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
细胞定位
Nucleus . Cytoplasm .
