FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
BNIP-3
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
22kD
MW(Observed)
22-28kD,50-55kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
PT0886R
特异性
Endogenous
基因名称
BNIP3
蛋白名称
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
别名
BNIP3;NIP3;BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
Organism-1
Human
基因ID-1
664
SwissProt-1
Q12983
Organism-2
Mouse
SwissProt-2
O55003
背景
This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. [provided by RefSeq, Dec 2014],
细胞定位
Mitochondrion. Mitochondrion outer membrane; Single-pass membrane protein. Coexpression with the EIB 19-kDa protein results in a shift in NIP3 localization pattern to the nuclear envelope. Colocalizes with ACAA2 in the mitochondria. Colocalizes with SPATA18 at the mitochondrion outer membrane.
