FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ULK1
反应性
Human,Mouse,Rat
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG, Kappa
偶联-Conjugate
Phospho
修饰-Modification
Ser556
MW(Calculated)
113kD
MW(Observed)
130kD
推荐稀释比
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
PT0907R
特异性
ULK1 (Phospho Ser556) Monoclonal Antibody detects endogenous levels of ULK1 around the phosphorylation site of S556 protein.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):LHsAP
基因名称
ULK1 KIAA0722
蛋白名称
ULK1 (Ser556)
别名
Serine/threonine-protein kinase ULK1;Autophagy-related protein 1 homolog;ATG1;hATG1;Unc-51-like kinase 1;
Organism-1
Human
基因ID-1
8408
SwissProt-1
O75385
Organism-2
Mouse
基因ID-2
22241
SwissProt-2
O70405
背景
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with GABARAP and GABARAPL2.,tissue specificity:Ubiquitously expressed. Detected in the following adult tissues: skeletal muscle, heart, pancreas, brain, placenta, liver, kidney, and lung.,
细胞定位
Cytoplasm, cytosol . Preautophagosomal structure . Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane that sequesters a portion of the cytoplasm resulting in the formation of an autophagosome. .
