FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Osteocalcin
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
11kD
MW(Observed)
22kD
推荐稀释比
IHC 1:2000-1:10000;WB 1:100-1:500;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆号
PT0763R
特异性
Endogenous
基因名称
BGLAP
蛋白名称
Osteocalcin (Bone Gla protein) (BGP) (Gamma-carboxyglutamic acid-containing protein)
Organism-1
Human
基因ID-1
632
SwissProt-1
P02818
Organism-2
Mouse
SwissProt-2
P86546
Organism-3
Rat
SwissProt-3
P04640
背景
This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015],
细胞定位
Secreted.
