- 产品信息
商品描述
靶点-Target
SQSTM1/p62
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
48kD
MW(Observed)
60kD
推荐稀释比
IHC 1:200-1000;WB 1:500-5000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0051R
特异性
Endogenous
基因名称
SQSTM1 ORCA OSIL
蛋白名称
SQSTM
Organism-1
Human
基因ID-1
8878
SwissProt-1
Q13501
Organism-2
Mouse
基因ID-2
18412
SwissProt-2
Q64337
Organism-3
Rat
基因ID-3
113894
SwissProt-3
O08623
背景
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009],
细胞定位
Cytoplasm, Nuclear





