FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PARP1
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
25kD
MW(Observed)
25kD
推荐稀释比
IHC 1:200-1000;WB 1:500-5000;IF 1:200-1000;ELISA 1:5000-20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0046R
特异性
This antibody detects endogenous levels of Cleaved PARP1.
基因名称
PARP1
蛋白名称
Poly [ADP-ribose] polymerase 1
别名
PARP1;ADPRT;PPOL;Poly [ADP-ribose] polymerase 1;PARP-1;ADP-ribosyltransferase diphtheria toxin-like 1;ARTD1;NAD;+;ADP-ribosyltransferase 1;ADPRT 1;Poly[ADP-ribose] synthase 1
Organism-1
Human
基因ID-1
142
SwissProt-1
P09874
Organism-2
Mouse
SwissProt-2
P11103
背景
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasmic, Nuclear
