FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PKM2
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
57kD
MW(Observed)
57kD
推荐稀释比
IHC 1:200-1000;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0080R
特异性
Endogenous
基因名称
PKM
蛋白名称
Pyruvate kinase isozymes M1/M2
别名
PKM;OIP3;PK2;PK3;PKM2;Pyruvate kinase isozymes M1/M2;Cytosolic thyroid hormone-binding protein;CTHBP;Opa-interacting protein 3;OIP-3;Pyruvate kinase 2/3;Pyruvate kinase muscle isozyme;Thyroid hormone-binding protein 1;THBP1;Tu
Organism-1
Human
基因ID-1
5315
SwissProt-1
P14618
Organism-2
Mouse
基因ID-2
18746
SwissProt-2
P52480
Organism-3
Rat
基因ID-3
25630
SwissProt-3
P11980
背景
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011],
细胞定位
Cytoplasm
