FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
IGF-1R
反应性
Human,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
154kD
MW(Observed)
200kD
推荐稀释比
IHC 1:100-200;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0136R
特异性
Endogenous
基因名称
IGF1R
蛋白名称
Insulin-like growth factor 1 receptor
别名
IGF1R;Insulin-like growth factor 1 receptor;Insulin-like growth factor I receptor;IGF-I receptor;CD antigen CD221
Organism-1
Human
基因ID-1
3480
SwissProt-1
P08069
Organism-2
Mouse
基因ID-2
16001
SwissProt-2
Q60751
Organism-3
Rat
基因ID-3
25718
SwissProt-3
P24062
背景
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],
细胞定位
Membranous
