FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CD105(Endoglin)
反应性
Human,
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
70kD
MW(Observed)
95kD
推荐稀释比
IHC 1:100-200;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0152R
特异性
Endogenous
基因名称
ENG END
蛋白名称
Endoglin (CD antigen CD105)
Organism-1
Human
基因ID-1
2022
SwissProt-1
P17813
背景
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013],
细胞定位
Cytoplasm
