FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Sp1
反应性
Human,
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
100kD
MW(Observed)
100kD
推荐稀释比
IHC 1:200-1000;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0149R
特异性
Endogenous
基因名称
SP1
蛋白名称
Transcription factor Sp1
别名
SP1;TSFP1;Transcription factor Sp1
Organism-1
Human
基因ID-1
6667
SwissProt-1
P08047
Organism-2
Mouse
基因ID-2
20683
SwissProt-2
O89090
Organism-3
Rat
基因ID-3
24790
SwissProt-3
Q01714
背景
The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014],
细胞定位
Nuclear
