FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MITF
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
58kD
MW(Observed)
58kD
推荐稀释比
IHC 1:200-500;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0106R
特异性
Endogenous
基因名称
MITF
蛋白名称
Microphthalmia-associated transcription factor
别名
MITF;BHLHE32;Microphthalmia-associated transcription factor;Class E basic helix-loop-helix protein 32;bHLHe32
Organism-1
Human
基因ID-1
4286
SwissProt-1
O75030
Organism-2
Mouse
基因ID-2
17342
SwissProt-2
Q08874
背景
This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
细胞定位
Nuclear
