- 产品信息
商品描述
靶点-Target
HDAC2
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
55kD
MW(Observed)
55kD
推荐稀释比
IHC 1:200-500;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0063R
特异性
Endogenous
基因名称
HDAC2
蛋白名称
Histone deacetylase 2
别名
HDAC2;Histone deacetylase 2;HD2
Organism-1
Human
基因ID-1
3066
SwissProt-1
Q92769
Organism-2
Mouse
基因ID-2
15182
SwissProt-2
P70288
背景
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010],
细胞定位
Nuclear





