FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
OPTN
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
63kD
MW(Observed)
74kD
推荐稀释比
IHC 1:200-500;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0197R
特异性
Endogenous
基因名称
OPTN FIP2 GLC1E HIP7 HYPL NRP
蛋白名称
OPTN
别名
Optineurin;E3-14.7K-interacting protein;FIP-2;Huntingtin yeast partner L;Huntingtin-interacting protein 7;HIP-7;Huntingtin-interacting protein L;NEMO-related protein;Optic neuropathy-inducing protein;Transcription factor IIIA-interacting protein;TFIIIA-IntP;
Organism-1
Human
基因ID-1
10133
SwissProt-1
Q96CV9
Organism-2
Mouse
基因ID-2
71648
SwissProt-2
Q8K3K8
Organism-3
Rat
基因ID-3
246294
SwissProt-3
Q8R5M4
背景
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
细胞定位
Cytoplasm
