Fibrillarin Rabbit mAb

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¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2621556

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商品描述
  • 靶点-Target

    FBL

  • 反应性

    Human,Mouse,Rat,

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG,Kappa

  • 偶联-Conjugate

    Unmodified

  • MW(Calculated)

    34kD

  • MW(Observed)

    34kD

  • 推荐稀释比

    IHC 1:200-1000;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein A

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    PT0195R

  • 特异性

    Endogenous

  • 基因名称

    FBL FIB1 FLRN

  • 蛋白名称

    rRNA 2'-O-methyltransferase fibrillarin (34 kDa nucleolar scleroderma antigen)

  • Organism-1

    Human

  • 基因ID-1

    2091

  • SwissProt-1

    P22087

  • Organism-2

    Mouse

  • 基因ID-2

    100044829

  • SwissProt-2

    P35550

  • Organism-3

    Rat

  • 基因ID-3

    292747

  • SwissProt-3

    P22509

  • 背景

    This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. [provided by RefSeq, Jul 2008]

  • 细胞定位

    Nucleus