- 产品信息
商品描述
靶点-Target
FBL
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
34kD
MW(Observed)
34kD
推荐稀释比
IHC 1:200-1000;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0195R
特异性
Endogenous
基因名称
FBL FIB1 FLRN
蛋白名称
rRNA 2'-O-methyltransferase fibrillarin (34 kDa nucleolar scleroderma antigen)
Organism-1
Human
基因ID-1
2091
SwissProt-1
P22087
Organism-2
Mouse
基因ID-2
100044829
SwissProt-2
P35550
Organism-3
Rat
基因ID-3
292747
SwissProt-3
P22509
背景
This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. [provided by RefSeq, Jul 2008]
细胞定位
Nucleus





