- 产品信息
商品描述
靶点-Target
HXK II
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
102kD
MW(Observed)
102kD
推荐稀释比
IHC 1:200-400;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0189R
特异性
Endogenous
基因名称
HK2
蛋白名称
Hexokinase-2
别名
HK2;Hexokinase-2;Hexokinase type II;HK II;Muscle form hexokinase
Organism-1
Human
基因ID-1
3099
SwissProt-1
P52789
Organism-2
Mouse
基因ID-2
15277
SwissProt-2
O08528
Organism-3
Rat
基因ID-3
25059
SwissProt-3
P27881
背景
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq, Apr 2009],
细胞定位
Cytoplasm





