FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Neuropilin
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
103kD
MW(Observed)
135kD
推荐稀释比
IHC 1:200-1000;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0182R
特异性
Endogenous
基因名称
NRP1
蛋白名称
Neuropilin-1
别名
NRP1;NRP;VEGF165R;Neuropilin-1;Vascular endothelial cell growth factor 165 receptor;CD antigen CD304
Organism-1
Human
基因ID-1
8829
SwissProt-1
O14786
Organism-2
Mouse
基因ID-2
18186
SwissProt-2
P97333
Organism-3
Rat
基因ID-3
246331
SwissProt-3
Q9QWJ9
背景
This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011],
细胞定位
Cytoplasmic, Membranous
