FGF-2 Polyclonal Antibody
¥680.00
Glucocorticoid Receptor Rabbit mAb
活动价：
¥880.00
市场价：¥1280.00
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产品规格：
- 50μL
货号：
FAB2621487
- 产品信息
商品描述
靶点-Target
Glucocorticoid Receptor
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
85kD
MW(Observed)
94kD
推荐稀释比
IHC 1:1000-1:4000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0306R
特异性
Endogenous
基因名称
Nr3c1 Grl Grl1
蛋白名称
Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)
别名
GCCR;GCR;GCR_HUMAN;GCRST;glucocorticoid nuclear receptor variant 1;Glucocorticoid receptor;GR;GRL;Grl1;nr3c1;Nuclear receptor subfamily 3 group C member 1;nuclear receptor subfamily 3, group C, member 1;glucocorticoid receptor;
Organism-1
Human
基因ID-1
2908
SwissProt-1
P04150
背景
This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011]
细胞定位
Nucleus
