- 产品信息
商品描述
靶点-Target
Survivin
反应性
Human,Mouse,Rat,
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
16kD
MW(Observed)
16kD
推荐稀释比
WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0343R
特异性
Endogenous
基因名称
>>Platinum drug resistance;>>Apoptosis;>>Apoptosis - multiple species;>>Hippo signaling pathway;>>Hepatitis B;>>Pathways in cancer;>>Chemical carcinogenesis - receptor activation;>>Colorectal cancer
蛋白名称
BIRC5
别名
BIRC5;API4;IAP4;Baculoviral IAP repeat-containing protein 5;Apoptosis inhibitor 4;Apoptosis inhibitor survivin
Organism-1
Human
基因ID-1
332
SwissProt-1
O15392
Organism-2
Mouse
基因ID-2
11799
SwissProt-2
O70201
Organism-3
Rat
基因ID-3
64041
SwissProt-3
Q9JHY7
背景
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011],
细胞定位
Nucleus





