- 产品信息
商品描述
靶点-Target
Claudin 1
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
22kD
MW(Observed)
19kD
推荐稀释比
IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0336R
特异性
Endogenous
基因名称
CLDN1
蛋白名称
Claudin-1
别名
CLDN1;CLD1;SEMP1;Claudin-1;Senescence-associated epithelial membrane protein
Organism-1
Human
基因ID-1
9076
SwissProt-1
O95832
Organism-2
Mouse
基因ID-2
12737
SwissProt-2
O88551
Organism-3
Rat
基因ID-3
65129
SwissProt-3
P56745
背景
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008],
细胞定位
Membrane





