Histone H2A.X (Phospho Ser139) Rabbit mAb

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¥880.00

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产品规格:
  • 50μL
货号:

FAB2621462

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商品描述
  • 靶点-Target

    Histone H2A.X

  • 反应性

    Human,Mouse,Rat,

  • 应用

    WB,IHC,IF,IP,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG,Kappa

  • 偶联-Conjugate

    Phospho

  • 修饰-Modification

    Ser139

  • MW(Calculated)

    15kD

  • MW(Observed)

    15kD

  • 推荐稀释比

    IHC 1:2000-1:8000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein A

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    PT0330R

  • 特异性

    This antibody detects endogenous levels of Histone H2A.X only when phosphorylated at Ser139.This antibody does not recognize phosphorylated at other sites.

  • 基因名称

    H2AFX

  • 蛋白名称

    Histone H2A.x

  • 别名

    H2AFX;H2AX;Histone H2A.x;H2a/x

  • Organism-1

    Human

  • 基因ID-1

    3014

  • SwissProt-1

    P16104

  • Organism-2

    Mouse

  • 基因ID-2

    15270

  • SwissProt-2

    P27661

  • 背景

    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015],

  • 细胞定位

    Nucleus