- 产品信息
商品描述
靶点-Target
Cytokeratin 8
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
54kD
MW(Observed)
54kD
推荐稀释比
IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0166R
特异性
Endogenous
基因名称
KRT8 CYK8
蛋白名称
CARD2;CK 8;CK-8;CK8;CYK8;CYKER;Cytokeratin endo A;Cytokeratin-8;DreK8;EndoA;K2C8;K2C8_HUMAN;K8;Keratin 8;Keratin type II cytoskeletal 8;Keratin, type II cytoskeletal 8;Keratin-8;KO;Krt 2.8;KRT8;MGC118110;MGC174782;MGC53564;MGC85764;sb:cb186;Type-II keratin Kb8
别名
CARD2;CK 8;CK-8;CK8;CYK8;CYKER;Cytokeratin endo A;Cytokeratin-8;DreK8;EndoA;K2C8;K2C8_HUMAN;K8;Keratin 8;Keratin type II cytoskeletal 8;Keratin, type II cytoskeletal 8;Keratin-8;KO;Krt 2.8;KRT8;MGC118110;MGC174782;MGC53564;MGC85764;sb:cb186;Type-II keratin Kb8
Organism-1
Human
基因ID-1
3856
SwissProt-1
P05787
Organism-2
Mouse
基因ID-2
16691
SwissProt-2
P11679
Organism-3
Rat
基因ID-3
25626
SwissProt-3
Q10758
背景
keratin 8(KRT8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],
细胞定位
Cytoplasm





