FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SLC7A11
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
37kD
MW(Observed)
55kD
推荐稀释比
IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0398R
特异性
Endogenous
基因名称
SLC7A11
蛋白名称
Cystine/glutamate transporter (Amino acid transport system xc-) (Calcium channel blocker resistance protein CCBR1) (Solute carrier family 7 member 11) (xCT)
别名
Cystine/glutamate transporter;Amino acid transport system xc-;Calcium channel blocker resistance protein CCBR1;Solute carrier family 7 member 11;xCT;
Organism-1
Human
基因ID-1
23657
SwissProt-1
Q9UPY5
Organism-2
Mouse
基因ID-2
26570
SwissProt-2
Q9WTR6
背景
This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
细胞定位
Membrane
