FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Tak1
反应性
Human,Mouse,Rat,
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
67kD
MW(Observed)
67kD
推荐稀释比
WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0396R
特异性
Endogenous
基因名称
MAP3K7
蛋白名称
Mitogen-activated protein kinase kinase kinase 7
别名
MAP3K7;TAK1;Mitogen-activated protein kinase kinase kinase 7;Transforming growth factor-beta-activated kinase 1;TGF-beta-activated kinase 1
Organism-1
Human
基因ID-1
6885
SwissProt-1
O43318
Organism-2
Mouse
基因ID-2
26409
SwissProt-2
Q62073
Organism-3
Rat
基因ID-3
100910771
SwissProt-3
P0C8E4
背景
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, Membrane
