FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
FTO
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
58kD
MW(Observed)
58kD
推荐稀释比
IHC 1:3000-1:20000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0383R
特异性
Endogenous
基因名称
FTO
蛋白名称
Alpha-ketoglutarate-dependent dioxygenase FTO
别名
FTO;KIAA1752;Alpha-ketoglutarate-dependent dioxygenase FTO;Fat mass and obesity-associated protein
Organism-1
Human
基因ID-1
79068
SwissProt-1
Q9C0B1
Organism-2
Mouse
基因ID-2
26383
SwissProt-2
Q8BGW1
Organism-3
Rat
基因ID-3
291905
SwissProt-3
Q2A121
背景
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011],
细胞定位
Cytoplasm, Nucleus
