- 产品信息
商品描述
靶点-Target
HDAC1
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
55kD
MW(Observed)
62kD
推荐稀释比
IHC 1:4000-1:10000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0390R
特异性
Endogenous
基因名称
HDAC1
蛋白名称
Histone deacetylase 1
别名
HDAC1;RPD3L1;Histone deacetylase 1;HD1
Organism-1
Human
基因ID-1
3065
SwissProt-1
Q13547
Organism-2
Mouse
基因ID-2
433759
SwissProt-2
O09106
Organism-3
Rat
基因ID-3
297893
SwissProt-3
Q4QQW4
背景
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus





