FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TGF β Receptor II
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
65kD
MW(Observed)
65kD
推荐稀释比
IHC 1:200-1:500;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0368R
特异性
Endogenous
基因名称
TGFBR2
蛋白名称
TGF-beta receptor type-2
别名
TGFBR2;TGF-beta receptor type-2;TGFR-2;TGF-beta type II receptor;Transforming growth factor-beta receptor type II;TGF-beta receptor type II;TbetaR-II
Organism-1
Human
基因ID-1
7048
SwissProt-1
P37173
Organism-2
Mouse
基因ID-2
21813
SwissProt-2
Q62312
Organism-3
Rat
基因ID-3
81810
SwissProt-3
P38438
背景
This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008],
细胞定位
Membrane
