FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Ubiquitin K48
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
26kD
MW(Observed)
13-250kD
推荐稀释比
IHC 1:200-1:1000;WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0424R
特异性
Endogenous
基因名称
UBA52/RPS27A/UBB/UBC
蛋白名称
Ubiquitin
别名
UBB;Polyubiquitin-B;UBC;Polyubiquitin-C;RPS27A;UBA80;UBCEP1;Ubiquitin-40S ribosomal protein S27a;Ubiquitin carboxyl extension protein 80;UBA52;UBCEP2;Ubiquitin-60S ribosomal protein L40;CEP52;Ubiquitin A-52 residue ribosomal pr;Ubiquitin K48;
Organism-1
Human
基因ID-1
7311
SwissProt-1
P0CG47;P0CG48;P62979;P62987
Organism-2
Mouse
基因ID-2
22187;22190;78294;22186
Organism-3
Rat
基因ID-3
192255;50522;100912032;64156
SwissProt-3
P0CG51;Q63429;P62982;P62986
背景
This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq
细胞定位
Cytoplasm
