- 产品信息
商品描述
靶点-Target
JAK3
反应性
Human,
应用
WB,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
125kD
MW(Observed)
125kD
推荐稀释比
WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0405R
特异性
Endogenous
基因名称
JAK3
蛋白名称
Tyrosine-protein kinase JAK3
别名
JAK3;Tyrosine-protein kinase JAK3;Janus kinase 3;JAK-3;Leukocyte janus kinase;L-JAK
Organism-1
Human
基因ID-1
3718
SwissProt-1
P52333
Organism-2
Mouse
基因ID-2
16453
SwissProt-2
Q62137
Organism-3
Rat
SwissProt-3
Q63272
背景
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm





