FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TGFB1\TGFB3
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
44kD
MW(Observed)
44kD,13kD
推荐稀释比
IHC 1:1000-1:4000;WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0402R
特异性
Endogenous
基因名称
TGFB1 TGFB3
蛋白名称
Transforming growth factor beta-1 proprotein;Latency-associated peptide(LAP);Transforming growth factor beta-1(TGF-beta-1);Transforming growth factor beta-3 proprotein;Transforming growth factor beta-3 (TGF-beta-3);
别名
Transforming growth factor beta-1 proprotein;Latency-associated peptide;LAP;Transforming growth factor beta-1;TGF-beta-1;Transforming growth factor beta-3 proprotein;Transforming growth factor beta-3;TGF-beta-3;
Organism-1
Human
基因ID-1
7040;7043
SwissProt-1
P01137;P10600
Organism-2
Mouse
基因ID-2
21803
SwissProt-2
P04202;P17125
Organism-3
Rat
基因ID-3
59086;25717
SwissProt-3
P17246;Q07258
背景
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic
细胞定位
Secreted
