- 产品信息
商品描述
靶点-Target
ACSL4
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
78kD
MW(Observed)
78kD
推荐稀释比
IHC 1:200-1:2000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0448R
特异性
Endogenous
基因名称
ACSL4 ACS4 FACL4 LACS4
蛋白名称
ACSL4
别名
Long-chain-fatty-acid--CoA ligase 4;Long-chain acyl-CoA synthetase 4;LACS 4;
Organism-1
Human
基因ID-1
2182
SwissProt-1
O60488
Organism-2
Mouse
基因ID-2
50790
SwissProt-2
Q9QUJ7
Organism-3
Rat
基因ID-3
113976
SwissProt-3
O35547
背景
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the cognitive disability or Alport syndrome. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq, Jan 2016]
细胞定位
Membrane





