- 产品信息
商品描述
靶点-Target
Notch 2
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
265kD
MW(Observed)
120kD
推荐稀释比
IHC 1:100-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0367R
特异性
Endogenous
基因名称
NOTCH2
蛋白名称
Neurogenic locus notch homolog protein 2
别名
NOTCH2;Neurogenic locus notch homolog protein 2;Notch 2;hN2
Organism-1
Human
基因ID-1
4853
SwissProt-1
Q04721
Organism-2
Mouse
基因ID-2
18129
SwissProt-2
O35516
Organism-3
Rat
基因ID-3
29492
SwissProt-3
Q9QW30
背景
notch 2(NOTCH2) Homo sapiens This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cle
细胞定位
Cytoplasm, Membrane





