- 产品信息
商品描述
靶点-Target
c-JUN
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
36kD
MW(Observed)
43kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0489R
特异性
Endogenous
基因名称
JUN
蛋白名称
C-Jun (Hydroxylated-p244); Transcription factor AP-1;jun;c-jun;AP-1
别名
Transcription factor AP-1 (Activator protein 1;AP1;Proto-oncogene c-Jun;V-jun avian sarcoma virus 17 oncogene homolog;p39)
Organism-1
Human
基因ID-1
3725
SwissProt-1
P05412
Organism-2
Mouse
基因ID-2
16476
SwissProt-2
P05627
Organism-3
Rat
基因ID-3
24516
SwissProt-3
P17325
背景
function:Transcription factor that recognizes and binds toThe enhancer heptamer motif 5'-TGA[CG]TCA-3'.,PTM:Phosphorylation enhancesThe transcriptional activity. Phosphorylated by PRKDC.,similarity:Belongs toThe bZIP family.,similarity:Belongs toThe bZIP family. Jun subfamily.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer with either FOS or BATF3. Interacts with HIVEP3 (By similarity). Interacts with SMAD3/SMAD4 heterodimers. Interacts with MYBBP1A, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibitsThe binding of active AP1 to its target DNA.,
细胞定位
Nucleus





