- 产品信息
商品描述
靶点-Target
Ezrin
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
69kD
MW(Observed)
80kD
推荐稀释比
IHC 1:1000-1:4000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0732R
特异性
Endogenous
基因名称
EZR
蛋白名称
Ezrin
别名
EZR;VIL2;Ezrin;Cytovillin;Villin-2;p81
Organism-1
Human
基因ID-1
7430
SwissProt-1
P15311
Organism-2
Mouse
基因ID-2
22350
SwissProt-2
P26040
Organism-3
Rat
基因ID-3
54319
SwissProt-3
P31977
背景
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, Membrane





