- 产品信息
商品描述
靶点-Target
Spectrin β II
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
275kD
MW(Observed)
275kD
推荐稀释比
IHC 1:1000-1:5000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0426R
特异性
Endogenous
基因名称
SPTBN1
蛋白名称
Spectrin beta chain non-erythrocytic 1
别名
SPTBN1;SPTB2;Spectrin beta chain; non-erythrocytic 1;Beta-II spectrin;Fodrin beta chain;Spectrin, non-erythroid beta chain 1
Organism-1
Human
基因ID-1
6711
SwissProt-1
Q01082
Organism-2
Mouse
基因ID-2
20742
SwissProt-2
Q62261
背景
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, Membrane





