- 产品信息
商品描述
靶点-Target
Syk
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
72kD
MW(Observed)
65kD
推荐稀释比
IHC 1:400-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0468R
特异性
Endogenous
基因名称
SYK
蛋白名称
Tyrosine-protein kinase SYK
别名
SYK;Tyrosine-protein kinase SYK;Spleen tyrosine kinase;p72-Syk
Organism-1
Human
基因ID-1
6850
SwissProt-1
P43405
Organism-2
Mouse
基因ID-2
20963
SwissProt-2
P48025
Organism-3
Rat
基因ID-3
25155
SwissProt-3
Q64725
背景
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],
细胞定位
Membrane





