- 产品信息
商品描述
靶点-Target
ATG5
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
33kD
MW(Observed)
55kD
推荐稀释比
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0514R
特异性
Endogenous
基因名称
ATG5 APG5L ASP
蛋白名称
ATG5
别名
Autophagy protein 5 (APG5-like;Apoptosis-specific protein)
Organism-1
Human
基因ID-1
9474
SwissProt-1
Q9H1Y0
Organism-2
Mouse
基因ID-2
11793
SwissProt-2
Q99J83
Organism-3
Rat
SwissProt-3
Q3MQ06
背景
The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2015],
细胞定位
Cytoplasm





