- 产品信息
商品描述
靶点-Target
YAP
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
55kD
MW(Observed)
55-75kD
推荐稀释比
IHC 1:100-1:500;WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0504R
特异性
Endogenous
基因名称
YAP1
蛋白名称
Yorkie homolog
别名
YAP1;YAP65;Yorkie homolog;65 kDa Yes-associated protein;YAP65
Organism-1
Human
基因ID-1
10413
SwissProt-1
P46937
Organism-2
Mouse
基因ID-2
22601
SwissProt-2
P46938
Organism-3
Rat
基因ID-3
363014
SwissProt-3
Q2EJA0
背景
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013],
细胞定位
Cytoplasm, Nucleus





