FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
VEGF-A
反应性
Human,Mouse,Rat,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG,Kappa
偶联-Conjugate
Unmodified
MW(Calculated)
27kD
MW(Observed)
40kD
推荐稀释比
IHC 1:1000-1:5000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0522R
特异性
Endogenous
基因名称
VEGFA
蛋白名称
Vascular endothelial growth factor A
别名
VEGFA;VEGF;Vascular endothelial growth factor A;VEGF-A;Vascular permeability factor;VPF
Organism-1
Human
基因ID-1
7422
SwissProt-1
P15692
Organism-2
Mouse
基因ID-2
22339
SwissProt-2
Q00731
Organism-3
Rat
基因ID-3
83785
SwissProt-3
P16612
背景
This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation fro
细胞定位
Secreted
